A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CLOCK
Type TF
Species Mus musculus
Tissue mice samples
Experiment Method qPCR
Up/Down Down
Pro/Anti Pro
Funtion Description Here we investigate the aging of mice deficient for CLOCK protein. Deficiency of the CLOCK protein significantly affects longevity: the average lifespan of Clock-/- mice is reduced by 15% compared with wild type mice, while maximum lifespan is reduced by
Regulation Gene NA
Year 2010
Pubmed ID 21149897
Title Deficiency of circadian protein CLOCK reduces lifespan and increases age-related cataract development in mice
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA