Details
| Name | c-Myb |
| Type | TF |
| Species | Homo sapiens |
| Tissue | fibroblasts |
| Experiment Method | PCR,other |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | The transcription factor c-Myb regulates OPN, IL-6, and IL-8 in addition to 57 other SASP factors. The regulation of OPN is direct as c-Myb binds to the OPN promoter in response to senescence. Further, OPN is also regulated by the known SASP regulator C/ |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 29416593 |
| Title | c-Myb and C/EBPB regulate OPN and other senescence-associated secretory phenotype factors. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |