A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name C-MYC
Type TF
Species Homo sapiens
Tissue NA
Experiment Method Southern blot
Up/Down Down
Pro/Anti Anti
Funtion Description The protooncogene c-myc positively regulates cellular proliferation whereas it exhibits negative effects on both cellular senescence and differentiation.
Regulation Gene c-myc
Year 1998
Pubmed ID 9521854
Title Accelerated proliferative senescence of rat embryo fibroblasts after stable transfection of multiple copies of the c-Myc DNA-binding sequence.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA