A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name crh-1
Type TF
Species Caenorhabditis elegans
Tissue C. elegans strains
Experiment Method Western Blot,RNAi
Up/Down Down
Pro/Anti Anti
Funtion Description We find that crh-1, the C. elegans homolog of the CREB transcription factor, is required for long-term associative memory, but not for learning or short-term memory. The expression of crh-1 declines with age and differs in the longevity mutants, and CREB
Regulation Gene NA
Year 2010
Pubmed ID 20502519
Title Insulin Signaling and Dietary Restriction Differentially Influence the Decline of Learning and Memory with Age
Drug NA
Disease NA
Environment Factors caloric restriction
Circulating NA
Variant snp
High-throughput NA