Details
| Name | CycD/Cdk4 |
| Type | TF |
| Species | Fly Strains |
| Tissue | Adult flies |
| Experiment Method | Western blotting;RT-PCR |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | We show that pan-neuronal loss or gain of CycD/Cdk4 increases mitochondrial superoxide, oxidative stress markers, and neurodegeneration and decreases lifespan.CycD/Cdk4's pathological consequences are mediated through altered mitochondrial function and a |
| Regulation Gene | NA |
| Year | 2015 |
| Pubmed ID | 26219626 |
| Title | Changes in neuronal CycD/Cdk4 activity affect aging, neurodegeneration, and oxidative stress. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |