Details
| Name | DAF-12 |
| Type | TF |
| Species | Caenorhabditis elegans |
| Tissue | somatic reproductive tissues |
| Experiment Method | qPCR |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | DAF-12-sterol signaling pathway has a second function to activate a distinct set of genes and extend lifespan in response to the somatic reproductive tissues. When germline-deficient animals lacking somatic reproductive tissues are given dafachronic acid, |
| Regulation Gene | cdr-6 |
| Year | 2010 |
| Pubmed ID | 20824162 |
| Title | The Somatic Reproductive Tissues of C. elegans Promote Longevity through Steroid Hormone Signaling |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | somatic mutation |
| High-throughput | NA |