A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name DAF-16
Type TF
Species Caenorhabditis elegans
Tissue C. elegans samples
Experiment Method qPCR
Up/Down NA
Pro/Anti NA
Funtion Description We show that specifically for gene activation, DAF-16/FOXO depends on SWI/SNF, facilitating SWI/SNF recruitment to target promoters, to activate transcription by presumed remodelling of local chromatin. For the animal, this translates into an essential ro
Regulation Gene NA
Year 2013
Pubmed ID 23604319
Title DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA