Details
| Name | DAF-16 |
| Type | TF |
| Species | Caenorhabditis elegans |
| Tissue | strains |
| Experiment Method | qPCR |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | Here, we challenge this view in C. elegans by showing that genetic programs actively promote longevity at cold temperatures. We find that TRPA-1, a cold-sensitive TRP channel, detects temperature drop in the environment to extend lifespan. This effect req |
| Regulation Gene | NA |
| Year | 2013 |
| Pubmed ID | 23415228 |
| Title | A genetic program promotes C. elegans longevity at cold temperatures via a thermosensitive TRP channel |
| Drug | NA |
| Disease | NA |
| Environment Factors | cold |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |