Details
| Name | DAF-16 |
| Type | TF |
| Species | Caenorhabditis elegans |
| Tissue | C. elegans strains |
| Experiment Method | genetic knockout |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | Our results indicate that OCC has the ability to ameliorate a-syn aggregation, reduce oxidative stress and promote longevity in C. elegans via activation of longevity promoting transcription factor DAF-16. Thus, OCC may serve as a lead compound of plant o |
| Regulation Gene | NA |
| Year | 2013 |
| Pubmed ID | 23244417 |
| Title | Iridoid compound 10-O-trans-p-coumaroylcatalpol extends longevity and reduces a synuclein aggregation in Caenorhabditis elegans |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |