A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name DAF-16
Type TF
Species Caenorhabditis elegans
Tissue C. elegans strains
Experiment Method other
Up/Down NA
Pro/Anti Anti
Funtion Description DAF-16 acts within a relatively small transcriptional subnetwork activating (but not suppressing) other regulators of stress resistance and aging, rather than directly regulating terminal effectors of longevity.
Regulation Gene akt-1,akt-2,coq-1,dao-3,hsp-12.6,mdl-1,skn-1
Year 2010
Pubmed ID 20706209
Title DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA