A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name DAF-16
Type TF
Species Caenorhabditis elegans
Tissue C. elegans strains
Experiment Method qPCR,RNAi
Up/Down NA
Pro/Anti Anti
Funtion Description Here we show that the somatic gonad and the germ cells make distinct contributions to life span determination. The life span increase produced by loss of the germ cells requires the DAF-16/FOXO transcription factor. In response to germ-cell removal, DAF-1
Regulation Gene SOD-3
Year 2008
Pubmed ID 18202391
Title Distinct activities of the germline and somatic reproductive tissues in the regulation of Caenorhabditis elegans' longevity.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA