A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Dctn1
Type gene
Species Mus musculus
Tissue nerve
Experiment Method PCR,other
Up/Down Down
Pro/Anti Pro
Funtion Description DCTN1 encodes p135 and other short splicing variants. The MTBDs of p150Glued are required for cell division by providing essential attachment to the microtubules in spindle formation and chromosome movement, p150Glued inhibition causes cell proliferation
Regulation Gene NA
Year 2018
Pubmed ID 29490687
Title Genetic ablation of dynactin p150Glued in postnatal neurons causes preferential degeneration of spinal motor neurons in aged mice
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA