A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name DAF-16
Type TF
Species Caenorhabditis elegans
Tissue cells
Experiment Method RNA interference
Up/Down Down
Pro/Anti Anti
Funtion Description Overall, we confirmed that transcription factor DAF-16 is neuroprotective in the proteotoxically stressed model, though not strikingly in the naturally aging model.Decreased daf-2 signaling slightly enhanced mechanosensation while greatly enhancing branch
Regulation Gene Insulin signaling
Year 2014
Pubmed ID 25101108
Title Insulin signaling in the aging of healthy and proteotoxically stressed mechanosensory neurons
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA