Details
| Name | E2F1 |
| Type | TF |
| Species | Homo sapiens |
| Tissue | DU145, LNCaP and PC3 cells |
| Experiment Method | qPCR |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | Importantly, it appears that E2F1 depletion-inducedcancercellsenescenceis not reliant on the integrity of either Rb or p53. Our results provide a molecular explanation for the selectivity with whichsenescenceinduction occurs, and also provides insights in |
| Regulation Gene | NA |
| Year | 2006 |
| Pubmed ID | 16596252 |
| Title | E2F-1 is a critical modulator of cellular senescence in human cancer. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |