Details
| Name | EGR1 |
| Type | TF |
| Species | Mus musculus |
| Tissue | embryo |
| Experiment Method | PCR, Western Analysis |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | We find that deletion of the early growth response 1(EGR1) transcription factor leads to a striking phenotype, including complete bypass of senescence and apparent immortal growth consistent with loss of a suppressor gene. |
| Regulation Gene | p53 |
| Year | 2003 |
| Pubmed ID | 12629205 |
| Title | Early growth response 1 protein, an upstream gatekeeper of the p53 tumor suppressor, controls replicative senescence. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |