| Name |
FOXM1
|
| Type |
TF
|
| Species |
Homo sapiens
|
| Tissue |
hepatocellular carcinoma cells
|
| Experiment Method |
RNAi,Western Blotting,qPCR
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
In the present study, we revealed that oxaliplatin could induce senescence in HCC cells, since advanced HCC patients with lower expression of FoxM1 were more sensitive to oxaliplatin therapy. Our data indicated that due to the repression by p53, FoxM1 pla
|
| Regulation Gene |
NA
|
| Year |
2013
|
| Pubmed ID |
23262037
|
| Title |
Negative regulation of transcription factor FoxM1 by p53 enhances oxaliplatin-induced senescence in hepatocellular carcinoma.
|
| Drug |
oxaliplatin
|
| Disease |
hepatocarcinoma
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|