A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name FOXM2B
Type TF
Species Mus musculus
Tissue liver
Experiment Method Western Blot
Up/Down Down
Pro/Anti Anti
Funtion Description Our results indicate that reduced expression of the FoxM1B transcription factor contributes to the decline in cellular proliferation observed in the aging process.
Regulation Gene cyclin B1 and cyclin D1 promoters
Year 2001
Pubmed ID 11572993
Title Increased levels of forkhead box M1B transcription factor in transgenic mouse hepatocytes prevent age-related proliferation defects in regenerating liver.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA