Details
| Name | FOXN1 |
| Type | TF |
| Species | Mus musculus |
| Tissue | thymic stromal cells |
| Experiment Method | Flow cytometry assay,qPCR |
| Up/Down | Up |
| Pro/Anti | Anti |
| Funtion Description | In aged mice, overexpression of Foxn1 in the thymus attenuated the decline in thymocyte numbers, prevented the decline in frequency of early thymic progenitors, and generated a higher number of signal joint TCR excised circle. Histologic studies revealed |
| Regulation Gene | NA |
| Year | 2011 |
| Pubmed ID | 21908422 |
| Title | Overexpression of Foxn1 attenuates age-associated thymic involution and prevents the expansion of peripheral CD4 memory T cells |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |