Details
| Name | FOXO |
| Type | TF |
| Species | Caenorhabditis elegans |
| Tissue | strains |
| Experiment Method | qPCR |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | NAD(+) is an important cofactor regulating metabolic homeostasis and a rate-limiting substrate for sirtuin deacylases. We show that NAD(+) levels are reduced in aged mice and Caenorhabditis elegans and that decreasing NAD(+) levels results in a further re |
| Regulation Gene | NA |
| Year | 2013 |
| Pubmed ID | 23870130 |
| Title | The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |