Details
| Name | FOXO |
| Type | TF |
| Species | Drosophila melanogaster |
| Tissue | Drosophila Strains |
| Experiment Method | Western Blotting,qPCR |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | The transcription factor FOXO and its target 4E-BP remove damaged proteins at least in part via the autophagy/lysosome system, whereas foxo mutants have dysfunctional proteostasis. Both FOXO and 4E-BP delay muscle functional decay and extend life span. Mo |
| Regulation Gene | 4E-BP |
| Year | 2010 |
| Pubmed ID | 21111239 |
| Title | FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |