Details
| Name | FOXO |
| Type | TF |
| Species | Caenorhabditis elegans |
| Tissue | C. elegans strains |
| Experiment Method | RNAi,qPCR |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | The accompanying increases in longevity are mediated largely through the activities of SKN-1 and the transcription factor DAF-16 (FOXO), which is required for longevity that derives from reduced IIS. Our results indicate that the SKN-1 detoxification gene |
| Regulation Gene | gcs-1 |
| Year | 2010 |
| Pubmed ID | 20700440 |
| Title | RNAi screening implicates a SKN-1-dependent transcriptional response in stress resistance and longevity deriving from translation inhibition. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |