A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name FOXO
Type TF
Species Drosophila melanogaster
Tissue NA
Experiment Method qPCR
Up/Down NA
Pro/Anti NA
Funtion Description dFoxO and 14-3-3E proteins interact in vivo and that this interaction is lost in response to oxidative stress. Loss of 14-3-3E results in increased stress-induced apoptosis, growth repression and extended lifespan of flies, phenotypes associated with elev
Regulation Gene NA
Year 2008
Pubmed ID 18665908
Title 14-3-3 Epsilon antagonizes FoxO to control growth, apoptosis and longevity in Drosophila.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA