Details
| Name | FOXO |
| Type | TF |
| Species | Caenorhabditis elegans |
| Tissue | C. elegans strains |
| Experiment Method | RNAi,qPCR |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | Expression of an active version of AMPK in worms increases stress resistance and extends longevity in a FOXO/DAF-16-dependent manner. Lastly, we find that AMPK activates FOXO/DAF-16-dependent transcription and phosphorylates FOXO/DAF-16 at previously unid |
| Regulation Gene | NA |
| Year | 2007 |
| Pubmed ID | 17900900 |
| Title | An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans. |
| Drug | NA |
| Disease | NA |
| Environment Factors | caloric restriction |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |