Details
| Name | FOXO1 |
| Type | TF |
| Species | Homo sapiens |
| Tissue | ovarian cancer cells |
| Experiment Method | Luciferase assay,qPCR |
| Up/Down | NA |
| Pro/Anti | NA |
| Funtion Description | To study PR action in OC in the absence of added estrogen (i.e., needed to induce robust PR expression), we created ES-2 OC cells stably expressing vector control or GFP-tagged PR-B (GFP-PR). Progestin (R5020) stimulation of ES-2 cells stably expressing G |
| Regulation Gene | NA |
| Year | 2013 |
| Pubmed ID | 23574718 |
| Title | Progesterone receptors induce FOXO1-dependent senescence in ovarian cancer cells |
| Drug | NA |
| Disease | ovarian cancer |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |