A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name FOXO1
Type TF
Species Mus musculus
Tissue mice
Experiment Method RT-PCR
Up/Down Down
Pro/Anti Anti
Funtion Description The MDA levels and SIRT2 expression in the colonic mucosa were significantly increased in the aged group when compared to the younger group. However, the levels of FoXO1 transcription factor were significantly decreased in the aged group. Melatonin signif
Regulation Gene SIRT2, NFkB and FoXO1
Year 2015
Pubmed ID 25430724
Title The role of melatonin, sirtuin2 and FoXO1 transcription factor in the aging process of colon in male rats
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA