Details
| Name | FOXO3a |
| Type | TF |
| Species | Mus musculus |
| Tissue | NA |
| Experiment Method | qPCR |
| Up/Down | NA |
| Pro/Anti | NA |
| Funtion Description | Here, we show that aging and myelosuppressive/growth-stimulating stress induce similar changes in FoxO3a-deficient HSCs, and that FoxO3a plays a central role in regulating maintenance of HSC function under conditions of stress and aging. |
| Regulation Gene | NA |
| Year | 2008 |
| Pubmed ID | 18799725 |
| Title | FoxO3a regulates hematopoietic homeostasis through a negative feedback pathway in conditions of stress or aging |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | 1 |
| Variant | NA |
| High-throughput | NA |