| Name |
FOXO3a
|
| Type |
TF
|
| Species |
Mus musculus
|
| Tissue |
Sixteen 3-month-old senescence-accelerated mouse-resistant 1 (SAMR1) and senescence-accelerated mouse-prone 8 (SAMP8) mice
|
| Experiment Method |
Immunohistochemistry;Western blotting
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
FOXO3a expression was significantly increased in the normally aged, air-exposed group compared with the aging-accelerated, air-exposed group. FOXO3a expression was significantly reduced in the aging-accelerated, smoke-exposed group compared with the aging
|
| Regulation Gene |
PI3K/Akt
|
| Year |
2015
|
| Pubmed ID |
26345785
|
| Title |
Smoking, aging, and expression of proteins related to the FOXO3 signaling pathway in lung tissues.
|
| Drug |
NA
|
| Disease |
chronic obstructive pulmonary disease
|
| Environment Factors |
smoking
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|