Details
| Name | GABA |
| Type | TF |
| Species | Caenorhabditis elegans |
| Tissue | Caenorhabditis elegans strains |
| Experiment Method | qRT-PCR |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | Deficiency in GABA signalling extends lifespan. This pro-longevity effect is mediated by the metabotropic GABAB receptor GBB-1, but not ionotropic GABAA receptors. GBB-1 regulates lifespan through G protein-PLCB signalling, which transmits longevity signa |
| Regulation Gene | NA |
| Year | 2015 |
| Pubmed ID | 26537867 |
| Title | Metabotropic GABA signalling modulates longevity in C. elegans. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |