A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name GATA
Type TF
Species Caenorhabditis elegans
Tissue C. elegans strains
Experiment Method RNAi,qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description We have identified a conserved Caenorhabditis elegans GATA transcription factor/MTA-1 homolog egr-1 (lin-40) that extends lifespan and promotes resistance to heat and UV stress when overexpressed. Expression of egr-1 increases with age, suggesting that it
Regulation Gene NA
Year 2014
Pubmed ID 24304470
Title The GATA transcription factor/MTA-1 homolog egr-1 promotes longevity and stress resistance in Caenorhabditis elegans
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA