| Name |
HBP1
|
| Type |
TF
|
| Species |
Homo sapiens
|
| Tissue |
cell lines (WI38, MDA-MB-231, MDA-MB-435, A549, NCI-H460, MDA-MB-468 and BT549)
|
| Experiment Method |
ChIP,qPCR
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
We report that the DNA-damaging agents doxorubicin and 7-ethyl-10-hydroxycamptothecin were able to induce the formation of SAHF in some tumour cell types, and this induction was accompanied by activation of the retinoblastoma protein pathway. By contrast,
|
| Regulation Gene |
NA
|
| Year |
2013
|
| Pubmed ID |
23859194
|
| Title |
Mitogen-activated protein kinase p38 and retinoblastoma protein signalling is required for DNA damage-mediated formation of senescence-associated heterochromatic foci in tumour cells
|
| Drug |
NA
|
| Disease |
tumor
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|