Details
| Name | HBP1 |
| Type | TF |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | qPCR,ChIP |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | HBP1 regulates the expression of the endogenous p16INK4A gene through direct sequence-specific binding. With HBP1 expression and the subsequent increase of p16INK4A gene expression, Ras induces premature senescence in primary cells. The data suggest a mod |
| Regulation Gene | p16 INK4A |
| Year | 2010 |
| Pubmed ID | 20581871 |
| Title | Transcriptional factor HBP1 targets P16INK4A, upregulating its expression and consequently is involved in Ras-induced premature senescence |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |