Details
| Name | HEL-1 |
| Type | TF |
| Species | Caenorhabditis elegans |
| Tissue | C. elegans strains |
| Experiment Method | qRT-PCR;Coimmunoprecipitation and Western Blot |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | Here, we report that a large fraction of RNA helicases regulate the lifespan of Caenorhabditis elegans. In particular, we show that a DEAD-box RNA helicase, helicase 1 (HEL-1), promotes longevity by specifically activating the DAF-16/forkhead box O (FOXO) |
| Regulation Gene | DAF-16/FOXO |
| Year | 2015 |
| Pubmed ID | 26195740 |
| Title | RNA helicase HEL-1 promotes longevity by specifically activating DAF-16/FOXO transcription factor signaling in Caenorhabditis elegans. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |