Details
| Name | HIF1A |
| Type | TF |
| Species | Mus musculus |
| Tissue | hyperoxic tissue |
| Experiment Method | ChIP |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | Using embryonic fibroblasts from a conditional HIF1a knockout mouse, we found that loss of HIF1a under aerobic conditions significantly accelerated the onset of cellular senescence, and decreased proliferation under hypoxia. Furthermore, we identify the m |
| Regulation Gene | MIF |
| Year | 2006 |
| Pubmed ID | 17142669 |
| Title | HIF1a delays premature senescence through the activation of MIF |
| Drug | NA |
| Disease | NA |
| Environment Factors | Oxidation |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |