A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name HSF1
Type TF
Species Yeast
Tissue Yeast strains
Experiment Method Immunoblotting
Up/Down Up
Pro/Anti Anti
Funtion Description We find that the short 25Q protein never aggregates whereas the long 103Q version always aggregates. However, the mid-size 47Q protein is soluble in young logarithmically growing yeast but aggregates as the yeast cells enter the stationary phase and age,
Regulation Gene NA
Year 2012
Pubmed ID 22970306
Title Aggregation of polyQ proteins is increased upon yeast aging and affected by Sir2 and Hsf1: novel quantitative biochemical and microscopic assays
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA