Details
| Name | HSF1 |
| Type | TF |
| Species | Homo sapiens |
| Tissue | skin fibroblasts |
| Experiment Method | qPCR |
| Up/Down | Up |
| Pro/Anti | Anti |
| Funtion Description | Here we demonstrate that HSR is suppressed in fibroblasts from the patients with segmental progerioid Werner Syndrome, which undergo premature senescence. Similar suppression of HSR was seen in normal fibroblasts, which underwent senescence in response to |
| Regulation Gene | NA |
| Year | 2012 |
| Pubmed ID | 22510478 |
| Title | The heat shock transcription factor Hsf1 is downregulated in DNA damage-associated senescence, contributing to the maintenance of senescence phenotype |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |