A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name HSF1
Type TF
Species Homo sapiens
Tissue fibroblasts
Experiment Method PCR,other
Up/Down Up
Pro/Anti Pro
Funtion Description Heat shock transcription factor 1 (HSF1) regulates the expression of a wide array of genes, controls the expression of heat shock proteins (HSPs) as well as cell senescence.
Regulation Gene NA
Year 2018
Pubmed ID 29632240
Title Acute HSF1 depletion induces cellular senescence through the MDM2-p53-p21 pathway in human diploid fibroblasts.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA