A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name HSF1
Type TF
Species Rat Rattus
Tissue hepatocytes
Experiment Method SDS-PAGE
Up/Down Up
Pro/Anti Pro
Funtion Description However, the decreased HSF1 binding activity to DNA is not due to reduced levels of HSF1 that are available for activation by heat shock. In fact, the levels of HSF1 are two- to threefold higher in hepatocytes from old rats, and the age-related increase i
Regulation Gene hsp70
Year 2000
Pubmed ID 10739655
Title Age-related alterations in the activation of heat shock transcription factor 1 in rat hepatocytes.
Drug NA
Disease NA
Environment Factors NA
Circulating 1
Variant NA
High-throughput NA