Details
| Name | HSF1 |
| Type | TF |
| Species | Caenorhabditis elegans |
| Tissue | strains |
| Experiment Method | RNAi,qPCR |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | Here, we demonstrate that the activation of heat shock factor 1 (HSF-1), a crucial longevity transcription factor known to act downstream of the insulin/IGF-1 signaling (IIS) pathway, mediates the prolonged lifespan conferred by mutations in C. elegans S6 |
| Regulation Gene | NA |
| Year | 2013 |
| Pubmed ID | 23879233 |
| Title | Heat shock factor 1 mediates the longevity conferred by inhibition of TOR and insulin/IGF-1 signaling pathways in C. elegans. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |