A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name dSir2
Type gene
Species Drosophila melanogaster
Tissue NA
Experiment Method qRT-pCR
Up/Down Down
Pro/Anti Pro
Funtion Description The dSir2 genes are closely related to aging. lifelong endurance exercise delays HFD-induced accelerated age-related locomotor impairment, cardiac dysfunction, death, and dSir2 expression decline, and prevents HFD-induced premature aging in Drosophila.
Regulation Gene NA
Year 2018
Pubmed ID 29484111
Title Endurance exercise prevents high-fat-diet induced heart and mobility premature aging and dsir2 expression decline in aging Drosophila
Drug 0
Disease NA
Environment Factors high-fat diet
Circulating NA
Variant NA
High-throughput NA