| Name |
mitochondrial transcription factor A
|
| Type |
TF
|
| Species |
Homo sapiens
|
| Tissue |
Retinal Pigment Epithelial Cells
|
| Experiment Method |
Immunoblot
|
| Up/Down |
NA
|
| Pro/Anti |
Anti
|
| Funtion Description |
Humanin treatment increased mitochondrial DNA copy number and upregulated mitochondrial transcription factor A, a key biogenesis regulator protein. Humanin protected RPE cells from oxidative stress-induced cell death by STAT3 phosphorylation and inhibitin
|
| Regulation Gene |
NA
|
| Year |
2016
|
| Pubmed ID |
26990160
|
| Title |
The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction.
|
| Drug |
Humanin
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|