A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name ins-6
Type TF
Species Caenorhabditis elegans
Tissue Caenorhabditis elegans strains
Experiment Method Quantitative real-time PCR
Up/Down NA
Pro/Anti Pro
Funtion Description A subset of sensory neurons shortens Caenorhabditis elegans' life span by differentially regulating the expression of a specific insulin-like peptide (ILP), INS-6.Notably, treatment with food-derived cues or optogenetic activation of sensory neurons signi
Regulation Gene ILP,INS-6
Year 2016
Pubmed ID 27125673
Title Food-derived sensory cues modulate longevity via distinct neuroendocrine insulin-like peptides.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA