A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Isl1
Type TF
Species Mus musculus
Tissue cochlear tissues
Experiment Method qPCR
Up/Down Up
Pro/Anti Anti
Funtion Description As the mice aged to 17 months, wild-type (WT) controls showed the progressive threshold elevation and outer hair cell loss characteristic of the age-related hearing loss (ARHL) in the background strain (C57BL/6J). In contrast, the Isl1 transgenic mice sho
Regulation Gene Isl1
Year 2013
Pubmed ID 24048839
Title Hair cell overexpression of Islet1 reduces age-related and noise-induced hearing loss
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA