A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name JunD
Type TF
Species Mus musculus
Tissue muscle tissues
Experiment Method qPCR
Up/Down NA
Pro/Anti Anti
Funtion Description Endothelium-dependent vasorelaxation was impaired in young and old JunD(-/-) mice (6 and 22 months old) compared with age-matched wild-type mice. JunD(-/-) mice displayed an age-independent decline in endothelial nitric oxide release and endothelial nitri
Regulation Gene NA
Year 2013
Pubmed ID 23410942
Title Deletion of the activated protein-1 transcription factor JunD induces oxidative stress and accelerates age-related endothelial dysfunction
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA