A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name JunD
Type TF
Species Homo sapiens
Tissue NA
Experiment Method Immunofluorescence and Immunoblotting
Up/Down NA
Pro/Anti Anti
Funtion Description The antiapoptotic role of JunD was confirmed using an in vivo model of TNF-mediated hepatitis. We propose that JunD protects cells from senescence, or apoptotic responses to stress stimuli, by acting as a modulator of the signaling pathways that link Ras
Regulation Gene NA
Year 2000
Pubmed ID 11106750
Title JunD protects cells from p53-dependent senescence and apoptosis.
Drug TNF
Disease hepatitis
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA