A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name MDT-15
Type TF
Species Caenorhabditis elegans
Tissue C. elegans strains
Experiment Method RNAi;qRT-PCR
Up/Down Up
Pro/Anti Anti
Funtion Description Here, we show that sterol regulatory element-binding protein (SREBP) and mediator-15 (MDT-15) prevent the life-shortening effects of a glucose-rich diet by regulating fat-converting processes in Caenorhabditis elegans.Up-regulation of the SREBP/MDT-15 tra
Regulation Gene NA
Year 2015
Pubmed ID 26637528
Title SREBP and MDT-15 protect C. elegans from glucose-induced accelerated aging by preventing accumulation of saturated fat.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA