A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name DUSP16
Type gene
Species Homo sapiens
Tissue fibroblasts
Experiment Method PCR, western blot
Up/Down Down
Pro/Anti NA
Funtion Description In particular, we showed that DUSP16 ablation leads to a G1/S transition arrest, reduced incorporation of 5-bromodeoxyuridine, enhanced senescence-associated B-galactosidase activity, and formation of senescence-associated heterochromatic foci. Mechanisti
Regulation Gene NA
Year 2015
Pubmed ID 26381291
Title DUSP16 ablation arrests the cell cycle and induces cellular senescence
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA