Details
| Name | Mtbp |
| Type | TF |
| Species | Mus musculus |
| Tissue | Mtbp+/ and littermate-matched Mtbp+/+ C57Bl/6 mice of both genders;Liver and gastrocnemius muscle of mice |
| Experiment Method | RT-PCR |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | Mtbp haploinsufficiency significantly increased longevity and maximal survival in mice. Reduced levels of Mtbp did not alter locomotor activity, litter size, or body size, but Mtbp heterozygous mice did exhibit elevated markers of metabolism, particularly |
| Regulation Gene | Myc |
| Year | 2016 |
| Pubmed ID | 27803394 |
| Title | Haploinsufficiency of the Myc regulator Mtbp extends survival and delays tumor development in aging mice. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | 1 |
| Variant | NA |
| High-throughput | NA |