A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name NFATC1
Type TF
Species Mus musculus
Tissue skin
Experiment Method qPCR,other
Up/Down Up
Pro/Anti Anti
Funtion Description Both NFATc1 alone and NFAT-Fos-Jun complexes can promote the expression of cytokines, such as IL-2, IL-3, and IL-4 (Macian et al., 2001). NFAT can cooperate with Smad/TGF-B and NF-kB in Ca2+/ calcineurin regulated transcription and controlled the expressi
Regulation Gene NA
Year 2018
Pubmed ID 29433674
Title Protective effect of dietary Alchemilla mollis on UVB-irradiated premature skin aging through regulation of transcription factor NFATc1 and Nrf2/ARE pathways.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA