| Name |
NFATC1
|
| Type |
TF
|
| Species |
Mus musculus
|
| Tissue |
Mouse (Mus musculus) strains;prostates from PCre/+;RT/+;TetO-NFATc1Nuc mice
|
| Experiment Method |
Immunostaining, and Western blotting;RT-PCR;
|
| Up/Down |
NA
|
| Pro/Anti |
Anti
|
| Funtion Description |
We found the upregulation of nuclear factor of activated T cells c1 (NFATc1) in human PCa and cultured PCa cells, but not in normal prostates and non-tumorigenic prostate cells.Our results indicate that the activation of a single transcription factor, NFA
|
| Regulation Gene |
p21
|
| Year |
2016
|
| Pubmed ID |
26477312
|
| Title |
NFATc1 promotes prostate tumorigenesis and overcomes PTEN loss-induced senescence.
|
| Drug |
NA
|
| Disease |
prostate cancer
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|