Details
| Name | NFE2L2 |
| Type | TF |
| Species | Mus musculus |
| Tissue | Mice VSMCs |
| Experiment Method | Western blotting;RT-PCR |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | Tissue-specific deletion of the essential autophagy gene Atg7 in murine VSMCs (atg7-/- VSMCs) caused accumulation of SQSTM1/p62 and accelerated the development of stress-induced premature senescence, CDKN2A-RB-mediated G1 proliferative arrest and senescen |
| Regulation Gene | NA |
| Year | 2015 |
| Pubmed ID | 26391655 |
| Title | Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis. |
| Drug | NA |
| Disease | cardiovascular disease |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |